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Anti-eNOS Polyclonal Antibody

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Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Clone:
Label:
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt) Canine (Ca) Bovine (Bv) Porcine (Po)
Immunogen: Synthetic peptide corresponding to the C-terminal domain of human eNOS.
Applications Dilution
Immunohistochemistry (Paraffin) (IHC (P)) Neat
Ordering Information
Pierce Anti-eNOS Polyclonal Antibody
Product Number Pkg Size Price


PA1-21014 7 ml $357.00
Storage: 4º C
Form: 7 ml of prediluted Immunogen affinity purified antibody in PBS; pH 7.4, 1% BSA, and 0.1% sodium azide.


Product Specific Information General Information
PA1-21014 detects eNOS in human, mouse, rat, bovine, canine, and porcine samples.

PA1-21014 has been successfully used in immunohistochemistry (paraffin) procedures.

The PA1-21014 immunogen is a synthetic peptide corresponding to the C-terminal domain of human eNOS.

Figure 1 illustrates immunohistochemical staining of eNOS in paraffin embedded human placental tissue using PA1-21014.
Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned. All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains.
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References:

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This product is for In Vitro experimental use only
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