| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide conjugated to KLH (aa sequence is considered to be commercially sensitive). |
| Ordering Information | ||||
| Pierce Anti-Lysophosphatidic Acid Receptor 4 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-20741 | 25 µg | $396.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 25 µg of Immunogen affinity purified (1 mg/ml) antibody in 0.01% Sodium Azide; PBS. pH 7.7 |
| Applications | Dilution |
| Immunocytochemistry (ICC) | Assay dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1/100 |
| Product Specific Information |
| PA1-20741 detects Lysophosphatidic Acid Receptor 4 in Human samples. PA1-20741 has been successfully used in Immunocytochemistry and Immunohistochemistry (Paraffin) procedures. PA1-20741 immunogen corresponds to Synthetic peptide conjugated to KLH (aa sequence is considered to be commercially sensitive).. |
| General Information |
| EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor, and leukocyte containing tissues. |
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Box 117, Rockford, IL 61105 USA |
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