| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide corresponding to a site midway between the cysteine switch and the zinc site of human MMP 7. |
| Ordering Information | ||||
| Pierce Anti-MMP7 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-20311 | 50 µg | $440.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 50 µg of Immunogen affinity purified (1 mg/ml) antibody in 15mM sodium azide; 50% Glycerol, 0.01M PBS. pH 7.4 |
| Applications | Dilution |
| ELISA (ELISA) | 1/1000 |
| Immunohistochemistry (IHC) | 1/1000 |
| Immunoprecipitation (IP) | 1/1000 |
| Western Blot (WB) | 1/1000 |
| Product Specific Information |
| PA1-20311 detects MMP-7 in human samples. PA1-20311 has been successfully used in ELISA, immunohistochemistry, immunoprecipitation and Western blot procedures. The PA1-20311 immunogen is a synthetic peptide corresponding to a site midway between the cysteine switch and the zinc site of human MMP 7. |
| General Information |
| Matrix Metalloproteinases (MMPs) belong to a family of proteases that are essential for the breakdown of extracellular matrix (ECM). They are thus important in apoptosis, tumor cell growth, invasion, and metastasis, as well as angiogenesis and wound healing. Most MMPs contain common domain structures that include a signal sequence, a propeptide, a catalytic domain, and a hemopexin-like (Hpx) domain. MMP7, also known as Matrilysin, is responsible for hydrolyzing proteoglycans and ECM glycoproteins. It is expressed in normal cells, specifically glandular epithelial cells. |
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Box 117, Rockford, IL 61105 USA |
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