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Anti-ADAMTS15 Polyclonal Antibody

Printable Datasheet

Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Clone:
Label:
Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide corresponding to residues C H(592) S T N R L T L A V A W(603) of human ADAMTS15.
Applications Dilution
Western Blot (WB) 1:1000
Ordering Information
Pierce Anti-ADAMTS15 Polyclonal Antibody
Product Number Pkg Size Price


PA1-1743 100 µg $350.00
Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 ug of epitope affinity purified rabbit IgG (1 mg/ml) in PBS containing 1 mg/ml BSA and 0.05% sodium azide


Product Specific Information General Information
PA1-1743 detects ADAMTS15 in human samples.

PA1-1743 has been successfully used in Western blot procedures. In Western blot analysis of 293EBNA cells this antibody detects a ~50 kDa protein representing ADAMTS15.

The PA1-1743 immunogen is a synthetic peptide corresponding to residues C H(592) S T N R L T L A V A W(603) of human ADAMTS15.

Figure 1 shows a Western blot of ADAMTS15 in 293EBNA cells using PA1-1743.
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The immunizing peptide sequence is 100% conserved between human, mouse and rat.

 
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