Anti-ADAMTS5 Polyclonal Antibody
| Host / Isotype: |
Rabbit |
| Class: |
Polyclonal |
| Type: |
Antibody |
| Clone: |
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| Label: |
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| Species Reactivity: |
Human (Hu) |
| Immunogen: |
Synthetic peptide corresponding to residues C I(442) L T S I D A S K P(451) of human ADAMTS5. |
|
| Pierce Anti-ADAMTS5 Polyclonal Antibody |
|
| Product Number |
Pkg Size |
Price |
|
|
| PA1-1742 |
100 µg |
$350.00 |
|
|
|
|
| Storage: |
-20º C, Avoid Freeze/Thaw Cycles |
| Form: |
100 ug of epitope affinity purified rabbit IgG (1 mg/ml) in PBS containing 1 mg/ml BSA and 0.05% sodium azide. |
PA1-1742 detects ADAMTS5 in human samples.
PA1-1742 has been successfully used in Western blot procedures. In Western blot analysis of JJ012 cells this antibody detects a ~64 kDa protein representing ADAMTS5.
The PA1-1742 immunogen is a synthetic peptide corresponding to residues C I(442) L T S I D A S K P(451) of human ADAMTS5.
Figure 1 shows a Western blot of ADAMTS5 in JJ012 cells using PA1-1742. |
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. |
No references for this product. |
This product is for In Vitro experimental use only
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