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Anti-ADAMTS5 Polyclonal Antibody

Synonyms:
A disintegrin and metalloproteinase with thrombospondin motifs 5, ADAM-TS 5, ADAM-TS5, Aggrecanase-2, ADMP-2, ADAM-TS 11
Entrez Gene ID:
(Human) 11096
UniProt ID:
Q9UNA0
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide corresponding to residues C I(442) L T S I D A S K P(451) of human ADAMTS5.
Ordering Information
Pierce Anti-ADAMTS5 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-1742 100 µg $350.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 ug of epitope affinity purified rabbit IgG (1 mg/ml) in PBS containing 1 mg/ml BSA and 0.05% sodium azide.


Applications Dilution
Western Blot (WB) 1:500
Product Specific Information
PA1-1742 detects ADAMTS5 in human samples.

PA1-1742 has been successfully used in Western blot procedures. In Western blot analysis of JJ012 cells this antibody detects a ~64 kDa protein representing ADAMTS5.

The PA1-1742 immunogen is a synthetic peptide corresponding to residues C I(442) L T S I D A S K P(451) of human ADAMTS5.

Figure 1 shows a Western blot of ADAMTS5 in JJ012 cells using PA1-1742.
General Information
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.
(This product is for In Vitro experimental use only.)


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