Anti-ADFP Polyclonal Antibody
Printable Datasheet
Synonyms:
Adipophilin antibody, adipose differentiation-related protein antibody, ADRP antibody
Entrez Gene ID:
(Human) 123
UniProt ID:
Q99541
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Murine (Ms) Non-human primate (Nhp) Bovine (Bv) Porcine (Po) |
| Immunogen: | Synthetic peptide corresponding to the internal region (within residues 150-250) of mouse ADFP. |
| Ordering Information | ||||
| Pierce Anti-ADFP Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-16971 | 100 µl | $285.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µl of peptide affinity purified rabbit antisera (0.98 mg/ml) in PBS with 30% glycerol. |
| Applications | Dilution |
| Western Blot (WB) | 2 µg/ml |
| Product Specific Information |
| PA1-16971 detects ADFP from human, monkey, porcine, murine and bovine samples. There is a 84% sequence identity with rat proteins. PA1-16971 has been successfully used in Western blot applications. By Western blot this antibody detects a ~48 kDa band, representing ADFP. The PA1-16971 immunogen is a synthetic peptide corresponding to the internal region (within residues 150-250) of mouse ADFP. Figure 1 illustrates Western blot detection of ADFP from human liver lysate using PA1-16971. |
| General Information |
| Milk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase. ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to specific cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. ADFP may be a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells. |
(This product is for In Vitro experimental use only.)
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