Anti-JAK1 Polyclonal Antibody
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Synonyms:
Tyrosine-protein kinase JAK1, Janus kinase 1, JAK1A, JAK1B
Entrez Gene ID:
(Human) 3716, (Murine) 16451, (Rat) 84598
UniProt ID:
P23458
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Murine (Ms) Rat (Rt) |
| Immunogen: | Synthetic phosphopeptide corresponding to human JAK1. |
| Ordering Information | ||||
| Pierce Anti-JAK1 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| PA1-14229 | 200 µg | $298.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 200 µg of antibody (1 mg/ml) in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications | Dilution |
| Immunohistochemistry (IHC) | 1:50 |
| Western Blot (WB) | 1:500 |
| Product Specific Information |
| PA1-14229 detects JAK1 in human, mouse and rat samples. PA1-14229 has been successfully used in Western blot and immunohisotchemistry procedures. The PA1-14229 immunogen is a synthesized phosphopeptide derived from human JAK1 around the phosphorylation site of tyrosine 1022 (K-E-Y-P-Y-T). |
| General Information |
| Janus Kinase 1 (JAK1) is one of a number of related tyrosine kinases involved in cytoplasmic signal transduction. In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at tyrosine residues. The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus. Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes. |
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Immunohistochemistry with anti-JAK1 Polyclonal Antibody (PA1-14229)
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(This product is for In Vitro experimental use only.)
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PO
Box 117, Rockford, IL 61105 USA |
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