Anti-ACCN2 Polyclonal Antibody
Printable Datasheet
Synonyms:
Acid-sensing ion channel 1, ASIC1, Brain sodium channel 2, BNaC2, ACCN2
Entrez Gene ID:
(Human) 41
UniProt ID:
Q2PH54
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Rat (Rt) |
| Immunogen: | Synthetic peptide from human and rat amiloride-sensitive cation channel 2, neuronal. |
| Ordering Information | ||||
| Pierce Anti-ACCN2 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| OSR00097W | 100 µl | $285.00 | ||
This product is available in North America and Europe only.
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µl lyophilized polyclonal antibody in whole serum. Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Applications | Dilution |
| Immunohistochemistry (IHC) | 1:300 |
| Western Blot (WB) | 1:300 |
| Product Specific Information |
| OSR00097W detects ACCN2 in Human and Rat samples. OSR00097W has been successfully used in Western blot and Immunohistochemistry applications. The OSR00097W immunogen is from a synthetic peptide corresponding to a portion of human and rat amiloride-sensitive cation channel 2, neuronal (ASIC1) conjugated to an immunogenic carrier protein. |
| General Information |
| This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown. Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Ca(2+), Li(+) and K(+). Expressed in dorsal root ganglia (DRG) and sciatic nerve (at protein level). Widely distributed throughout the brain. Expressed in olfactory bulb, neo and allocortical regions, dentate granule cells, pyramidal cells of CA1-CA3 subfields of the hippocampal formation, habenula, basolateral amygdaloid nuclei, and in the Purkinje and granule cells of the cerebellum. Diffusely detected over most other regions of the basal ganglia, including thalamic nuclei, substantia nigra, striatum and globus pallidus, hypothalamus, midbrain, pons, medulla and choroid plexus. Isoform 3 is expressed only in dorsal root ganglion while isoform 1 is expressed in DRG, spinal chord, trigeminal ganglia and the trigeminal mesencephalic nucleus.; |
(This product is for In Vitro experimental use only.)
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PO
Box 117, Rockford, IL 61105 USA |
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