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TRACE AMINE-ASSOCIATED RECEPTOR 1 ANTIBODIES > TRACE AMINE-ASSOCIATED RECEPTOR 1 POLYCLONAL ANTIBODY OSR00079W
Anti-Trace Amine-Associated Receptor 1 Polyclonal Antibody
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Synonyms:
Trace amine receptor 1, TaR-1, TA1, TAR1, TRAR1
Entrez Gene ID:
(Human) 134864
UniProt ID:
Q9BXE9
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide from human TAAR1 conjugated to immunogenic carrier Protein. |
| Ordering Information | ||||
| Pierce Anti-Trace Amine-Associated Receptor 1 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| OSR00079W | 100 µl | $285.00 | ||
This product is available in North America and Europe only.
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µl lyophilized polyclonal antibody in whole serum. Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Applications | Dilution |
| Immunohistochemistry (IHC) | 1:300 |
| Western Blot (WB) | 1:300 |
| Product Specific Information |
| OSR00079W detects Trace amine-associated Receptor 1 in Human samples. OSR00079W has been successfully used in Western blot and Immunohistochemistry applications. The OSR00079W immunogen is from a synthetic peptide corresponding to a portion of human TAAR1 conjugated to an immunogenic carrier protein. |
| General Information |
| Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase. Detected in low levels in discrete regions within the central nervous system and in several peripheral tissues. Moderately expressed in stomach. Low levels in amygdala, kidney, and lung, and small intestin. Trace amounts in cerebellum, dorsal root ganglia, hippocampus, hypothalamus, liver, medulla, pancreas, pituitary, pontine reticular formation, prostate, skeletal muscle, and spleen. |
(This product is for In Vitro experimental use only.)
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