| Details | |
| Host / Isotype: | Mouse |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | R1JHL |
| Species Reactivity: | Human (Hu) Murine (Ms) Rat (Rt) |
| Immunogen: | Fusion protein corresponding to amino acids 1-564 of rat NMDA NR1. |
| Ordering Information | ||||
| Pierce Anti-NMDA Receptor 1 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| OMA1-04010 | 15 µg | $339.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 15 µg of lyophilized affinity purified antibody. The antibody should be reconstituted in 50µl of phosphate buffered saline (137mM NaCl, 7.5mM Na2HPO4, 2.7mM KCl, 1.5mM KH2PO4, pH 7.4) before use. |
| Applications | Dilution |
| Immunoprecipitation (IP) | 3 µg/200µg lysate |
| Western Blot (WB) | 1:300 |
| Product Specific Information |
| OMA1-04010 detects N-methyl-D-aspartate (NMDA) receptor type 1 subunit (NR1) from human, mouse, and rat tissues. This antibody shows no cross-reactivity with any of the NR2 subunits. OMA1-04010 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects a single ~120 kDa protein representing NR1 in rat brain homogenate. OMA1-04010 antigen is a fusion protein corresponding to amino acids 1-564 from rat NR1. |
| General Information |
| The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. |
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