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Anti-NMDA Receptor 1 Monoclonal Antibody

Synonyms:
NR1, N-Methyl-D-Aspartate Receptor
Entrez Gene ID:
(Human) 2902, (Murine) 14810, (Rat) 24408
UniProt ID:
Q05586
Details
Host / Isotype: Mouse
Class: Monoclonal
Type: Antibody
Clone: R1JHL
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt)
Immunogen: Fusion protein corresponding to amino acids 1-564 of rat NMDA NR1.
Ordering Information
Pierce Anti-NMDA Receptor 1 Monoclonal Antibody
Product Number Pkg. Size Price Purchase
OMA1-04010 15 µg $339.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 15 µg of lyophilized affinity purified antibody. The antibody should be reconstituted in 50µl of phosphate buffered saline (137mM NaCl, 7.5mM Na2HPO4, 2.7mM KCl, 1.5mM KH2PO4, pH 7.4) before use.


Applications Dilution
Immunoprecipitation (IP) 3 µg/200µg lysate
Western Blot (WB) 1:300
Product Specific Information
OMA1-04010 detects N-methyl-D-aspartate (NMDA) receptor type 1 subunit (NR1) from human, mouse, and rat tissues. This antibody shows no cross-reactivity with any of the NR2 subunits.

OMA1-04010 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects a single ~120 kDa protein representing NR1 in rat brain homogenate.

OMA1-04010 antigen is a fusion protein corresponding to amino acids 1-564 from rat NR1.
General Information
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
(This product is for In Vitro experimental use only.)


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