Anti-RAB9 Monoclonal Antibody
| Host / Isotype: |
Mouse / IgG1 |
| Class: |
Monoclonal |
| Type: |
Antibody |
| Clone: |
Mab9 |
| Label: |
|
| Species Reactivity: |
Human (Hu) Rat (Rt) Canine (Ca) Non-human primate (Nhp) Bovine (Bv) Hamster (Hm) |
| Immunogen: |
Recombinant canine rab 9a. |
|
| Immunocytochemistry (ICC) |
1:500 |
| Immunofluorescence (IF) |
1:500 |
| Immunoprecipitation (IP) |
Assay dependent |
| Western Blot (WB) |
1:1,000 |
| Pierce Anti-RAB9 Monoclonal Antibody |
|
| Product Number |
Pkg Size |
Price |
|
|
| MA3-067 |
100 µl |
$354.00 |
|
|
|
|
| Storage: |
-20º C, Avoid Freeze/Thaw Cycles |
| Form: |
100 µl of PBS-diluted ascites containing 0.05% sodium azide. |
MA3-067 recognizes prenylated and non-prenylated rab 9 from canine, human, monkey, rat, hamster and bovine tissues. This antibody does not cross-react with other rab family members.
MA3-067 has been successfully used in Western blot, immunofluorescence, EM immunocytochemistry and immunoprecipitation procedures. By Western blot, this antibody detects an ~26 kDa protein representing rab 9 from K562 cell extract.
The MA3-067 antigen is recombinant canine rab 9a. |
Rab proteins are a family of Ras-like GTPases involved in intracellular compartment protein transport. Different members of the 40+ member rab family are responsible for docking and fusion of transport vesicles between different compartments within the cell. Rab 9 is required for trafficking mannose 6-phosphate receptor between the late endosome to trans-Golgi network (TGN). By facilitating receptor transport, rab 9 enables cells to efficiently recycle important cellular trafficking components.
It is functionally necessary for rab 9, like other rab family members, to be prenylated by two 20-carbon geranylgeranyl groups at the C-terminus. Most prenylated rab 9 is membrane bound, however, 10-20% of the cellular pool of rab 9 is bound to GDP dissociation inhibitor-alpha (GDI-alpha) in the cytosol. GDI recycles prenylated, GDP bound rab 9 from their fusion targets back to their membranes of origin. |
This product is for In Vitro experimental use only
Printable Datasheet
