Anti-RAB9 Monoclonal Antibody
Printable Datasheet
Synonyms:
Ras-related protein Rab-9
Entrez Gene ID:
(Human) 9367
UniProt ID:
P51151
| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | Mab9 |
| Species Reactivity: | Human (Hu) Rat (Rt) Canine (Ca) Non-human primate (Nhp) Bovine (Bv) Hamster (Hm) |
| Immunogen: | Recombinant canine rab 9a. |
| Ordering Information | ||||
| Pierce Anti-RAB9 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA3-067 | 100 µl | $354.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µl of PBS-diluted ascites containing 0.05% sodium azide. |
| Applications | Dilution |
| Immunocytochemistry (ICC) | 1:500 |
| Immunofluorescence (IF) | 1:500 |
| Immunoprecipitation (IP) | Assay dependent |
| Western Blot (WB) | 1:1,000 |
| Product Specific Information |
| MA3-067 recognizes prenylated and non-prenylated rab 9 from canine, human, monkey, rat, hamster and bovine tissues. This antibody does not cross-react with other rab family members. MA3-067 has been successfully used in Western blot, immunofluorescence, EM immunocytochemistry and immunoprecipitation procedures. By Western blot, this antibody detects an ~26 kDa protein representing rab 9 from K562 cell extract. The MA3-067 antigen is recombinant canine rab 9a. |
| General Information |
| Rab proteins are a family of Ras-like GTPases involved in intracellular compartment protein transport. Different members of the 40+ member rab family are responsible for docking and fusion of transport vesicles between different compartments within the cell. Rab 9 is required for trafficking mannose 6-phosphate receptor between the late endosome to trans-Golgi network (TGN). By facilitating receptor transport, rab 9 enables cells to efficiently recycle important cellular trafficking components. It is functionally necessary for rab 9, like other rab family members, to be prenylated by two 20-carbon geranylgeranyl groups at the C-terminus. Most prenylated rab 9 is membrane bound, however, 10-20% of the cellular pool of rab 9 is bound to GDP dissociation inhibitor-alpha (GDI-alpha) in the cytosol. GDI recycles prenylated, GDP bound rab 9 from their fusion targets back to their membranes of origin. |
(This product is for In Vitro experimental use only.)
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Box 117, Rockford, IL 61105 USA |
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