| Details | |
| Host / Isotype: | Mouse / IgM |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | M4110421 |
| Species Reactivity: | Human (Hu) Murine (Ms) Bovine (Bv) |
| Immunogen: | Human Angiotensin Converting Enzyme |
| Ordering Information | ||||
| Pierce Anti-ACE DISCONTINUED Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-90876 | 50 µg | $0.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 50 µg of antibody in PBS, pH 7.4. |
| Applications | Dilution |
| Flow Cytometry (FACS) | Assay dependent |
| Flow Cytometry (FACS) | Assay dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay dependent |
| Product Specific Information |
| MA1-90876 detects ACE from mouse, human, bovine samples. MA1-90876 has been successfully used in flow cytometry, immunohistochemistry (frozen tissue), immunohistochemistry (paraffin tissue) applications. The MA1-90876 immunogen is: Human Angiotensin Converting Enzyme |
| General Information |
| This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
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