| Details | |
| Host / Isotype: | Mouse / IgM |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | 100-1A5 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Human activated leucocytes |
| Ordering Information | ||||
| Pierce Anti-CD1b DISCONTINUED Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-90450 | 500 µl | $0.00 | ||
| Storage: | 4º C |
| Form: | 500 µl of ammonium sulfate precipitation purified antibody in PBS, pH 7.4, 0.2% BSA with 0.09% sodium azide. |
| Applications | Dilution |
| Immunofluorescence (IF) | Assay dependent |
| Product Specific Information |
| MA1-90450 detects CD1b from human samples. MA1-90450 has been successfully used in immunofluorescence applications. The MA1-90450 immunogen is: Human activated leucocytes |
| General Information |
| This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. |
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