| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | UJ127.11 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Tissue preparation: Homogenous suspension of human fetal brain |
| Ordering Information | ||||
| Pierce Anti-L1CAM Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-90047 | 100 µg | $393.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of IgG fraction in 0.01 M PBS, pH 7.4 with 15 mM sodium azide. |
| Applications | Dilution |
| Immunohistochemistry (IHC) | Assay dependent |
| Immunoprecipitation (IP) | Assay dependent |
| Western Blot (WB) | 0.25-0.5 µg/ml |
| Product Specific Information |
| MA1-90047 detects L1CAM from human samples. MA1-90047 has been successfully used in immunohistochemistry, immunoprecipitation, Western blot applications. The MA1-90047 immunogen is: Tissue preparation: Homogenous suspension of human fetal brain |
| General Information |
| The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. |
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Box 117, Rockford, IL 61105 USA |
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