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Anti-RYK Monoclonal Antibody

Printable Datasheet

Details
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Clone: F35 P7 D7 F5
Label:
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt)
Immunogen: Synthetic peptide corresponding to residues C(462) L T E F H A A L G A Y V(475) of RYK, conjugated to ovalbumin.
Applications Dilution
Western Blot (WB) 2 ug/mL
Ordering Information
Pierce Anti-RYK Monoclonal Antibody
Product Number Pkg Size Price


MA1-615 100 µg $354.00
Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 ug of protein G purified IgG (1 mg/ml) antibody in PBS with 1 mg/ml BSA and 0.05% sodium azide.


Product Specific Information General Information
This antibody detects RYK in human, mouse, and rat samples.

MA1-615 has been successfully used in Western blot, procedures. By Western blot this antibody detects the RYK receptor-like tyrosine kinase-1 in cells.

The MA1-615 immunogen corresponds to the ovalbumin-conjugated synthetic peptide C (462) L T E F H A A L G A Y V(475).

Figure 1 shows a Western blot of RYK using MA1-615 in HCT116 cells lysate.
RYK (Receptor-like Tyrosine kinase-1) is in the Tyrosine family of receptor kinases. It is found in the plasma membrane of heart, prostate and kidney cells. RYK contains 604 amino acids and has an approximate molecular weight of 67507 Da. It contains one WIF domain. It functions as a potential growth factor receptor protein tyrosine kinase. RYK are divergent from those of other classic receptor tyrosine kinases. It is an orphan receptor that contains a catalytically inactive tyrosine-kinase-related domain. RYK is expressed in nestin-positive progenitor cells and neurons, and in a certain population of oligodendrocytes, O-2A progenitor cells, and type-2 astrocytes in developing CNS.
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References:

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