Anti-RYK Monoclonal Antibody
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Synonyms:
RYK1, Receptor-like tyrosine kinase, D3S3195, ERK3, Hydroxyaryl-protein kinase
Entrez Gene ID:
(Human) 6259, (Murine) 20187, (Rat) 140585
UniProt ID:
P34925
| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | F35 P7 D7 F5 |
| Species Reactivity: | Human (Hu) Murine (Ms) Rat (Rt) |
| Immunogen: | Synthetic peptide corresponding to residues C(462) L T E F H A A L G A Y V(475) of RYK, conjugated to ovalbumin. |
| Ordering Information | ||||
| Pierce Anti-RYK Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-615 | 100 µg | $354.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 ug of protein G purified IgG (1 mg/ml) antibody in PBS with 1 mg/ml BSA and 0.05% sodium azide. |
| Applications | Dilution |
| Western Blot (WB) | 2 ug/mL |
| Product Specific Information |
| This antibody detects RYK in human, mouse, and rat samples. MA1-615 has been successfully used in Western blot, procedures. By Western blot this antibody detects the RYK receptor-like tyrosine kinase-1 in cells. The MA1-615 immunogen corresponds to the ovalbumin-conjugated synthetic peptide C (462) L T E F H A A L G A Y V(475). Figure 1 shows a Western blot of RYK using MA1-615 in HCT116 cells lysate. |
| General Information |
| RYK (Receptor-like Tyrosine kinase-1) is in the Tyrosine family of receptor kinases. It is found in the plasma membrane of heart, prostate and kidney cells. RYK contains 604 amino acids and has an approximate molecular weight of 67507 Da. It contains one WIF domain. It functions as a potential growth factor receptor protein tyrosine kinase. RYK are divergent from those of other classic receptor tyrosine kinases. It is an orphan receptor that contains a catalytically inactive tyrosine-kinase-related domain. RYK is expressed in nestin-positive progenitor cells and neurons, and in a certain population of oligodendrocytes, O-2A progenitor cells, and type-2 astrocytes in developing CNS. |
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Western Blot with anti-RYK Monoclonal Antibody [F35 P7 D7 F5] (MA1-615)
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(This product is for In Vitro experimental use only.)
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PO
Box 117, Rockford, IL 61105 USA |
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