Anti-AKT3 Monoclonal Antibody
Printable Datasheet
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Synonyms:
DKFZp434N0250, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2
Entrez Gene ID:
(Human) 10000, (Murine) 23797, (Rat) 29414
UniProt ID:
Q9Y243
| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | 66C1247.1 |
| Species Reactivity: | Human (Hu) Murine (Ms) Rat (Rt) |
| Immunogen: | Human Akt3. |
| Ordering Information | ||||
| Pierce Anti-AKT3 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-41201 | 100 µg | $285.00 | ||
| Storage: | -20°C |
| Form: | 100 µg antibody in 200 µl PBS containing 0.02% sodium azide, 100 µg/ml BSA. |
| Applications | Dilution |
| Western Blot (WB) | 1-2 µg/ml |
| Product Specific Information |
| MA1-41201 detects AKT3 in human, rat and murine samples. MA1-41201 has been successfully used in Western blot applications. MA1-41201 is derived from a synthetic peptide corresponding to amino acid residues 119-136 (CSPTSQIDNIGEEEMDaS) of human akt3, GenBank no. AF135794_1. This sequence is identical in human, mouse, rat, cow, dog, and chicken. |
| General Information |
| Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activat phosphtidylinositol 3-kinase (PI 3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI-3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). Akt1, 2 and 3 contain a key regulatory serine phosphorylation site in the carboxy-terminal region of the protein. Akt/PKB phosphorylation is critical for it activity. |
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Western Blot with anti-AKT3 Monoclonal Antibody [66C1247.1] (MA1-41201)
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(This product is for In Vitro experimental use only.)
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PO
Box 117, Rockford, IL 61105 USA |
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