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GALECTIN 3 ANTIBODIES > GALECTIN 3 MONOCLONAL ANTIBODY MA1-40229
Anti-Galectin 3 Monoclonal Antibody
Printable Datasheet
Synonyms:
LGALS3
Entrez Gene ID:
(Human) 8484
UniProt ID:
O60755
| Details | |
| Host / Isotype: | mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | B2C10 |
| Species Reactivity: | Human (Hu) Murine (Ms) |
| Immunogen: | First 45 residues of human Galectin-3. |
| Ordering Information | ||||
| Pierce Anti-Galectin 3 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-40229 | 100 µg | $478.00 | ||
| Storage: | 4º C |
| Form: | 1 ml (100 µg/ml) of 0.2 um filtered antibody solution in PBS containing 0.02% sodium azide and 0.1% BSA. |
| Applications | Dilution |
| ELISA (ELISA) | Assay Dependent |
| Flow Cytometry (FACS ) | Assay Dependent. |
| Functional Assay (FN) | Assay Dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay Dependent. |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay Dependent. |
| Western Blot (WB) | Assay Dependent. |
| Product Specific Information |
| MA1-40229 detects Galectin-3 from human and mouse samples. This antibody does not cross react with Galedin-3C and is cross reactive with mouse galectin-3. MA1-40229 has been successfully used in flow cytometry, immunohistochemistry (frozen), immunohistochemistry (paraffin), functional assays, ELISA and Western blot applications. The MA1-40229 immunogen is the first 45 residues of human Galectin-3. |
| General Information |
| The monolonal antibody B2C10 reacts with galectin-3, a 30 kDa protein. Galectin-3 is a member of the galectin family. The protein is compose of three domains: a small amino-terminal domain, a carboxyl-terminal carbohydrate recognition domain (CRD) and amino-terminal domain containing repeating elements. Galectin-3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. The expression is also affected by neoplastic transformation: up-regulated in certain types of lymphomas and thyroid carcinoma, while down-regulated in other types of malignancies, such as colon, breast, ovarian and uterine carcinomas. |
(This product is for In Vitro experimental use only.)
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