Anti-XRCC1 Monoclonal Antibody
Printable Datasheet
Synonyms:
x-ray cross complementing
Entrez Gene ID:
(Human) 7515
UniProt ID:
P18887
| Details | |
| Host / Isotype: | Mouse |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | SPM327 |
| Species Reactivity: | Human (Hu) Rat (Rt) |
| Immunogen: | Recombinant human XRCC1 protein. |
| Ordering Information | ||||
| Pierce Anti-XRCC1 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-38877 | 7 ml | $268.00 | ||
| Storage: | 4ยบ C |
| Form: | 7 ml of prediluted antibody. |
| Applications | Dilution |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay Dependent |
| Product Specific Information |
| MA1-38877 detects XRCC1 from human and rat samples. MA1-38877 has been successfully used in immunohistochemistry (paraffin) applications. The MA1-38877 immunogen is recombinant human XRCC1 protein. |
| General Information |
| X-Ray Repair Cross Complementing (XRCC1) plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase beta through the N-terminal half. In testis XRCC1 is expressed at high levels. Cells with a mutation of this gene exhibit decreased single strand break repair and reduced recombination repair. They show increased double strand breaks, and sister chromatin exchange is increased up to 10-fold. The XRCC1 might serve as a scaffold protein during base excision-repair. |
(This product is for In Vitro experimental use only.)
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PO
Box 117, Rockford, IL 61105 USA |
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