Anti-XPA Monoclonal Antibody
Printable Datasheet
Synonyms:
xeroderma pigmentosum group A
Entrez Gene ID:
(Human) 7507
UniProt ID:
P23025
| Details | |
| Host / Isotype: | Mouse |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | SPM326 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Recombinant human XPA protein. |
| Ordering Information | ||||
| Pierce Anti-XPA Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-38872 | 7 ml | $268.00 | ||
| Storage: | 4ยบ C |
| Form: | 7 ml of prediluted antibody. |
| Applications | Dilution |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay Dependent |
| Product Specific Information |
| MA1-38872 detects XPA from human samples. MA1-38872 has been successfully used in immunohistochemistry (paraffin) applications. The MA1-38872 immunogen is recombinant human XPA protein. |
| General Information |
| The XPA (xeroderma pigmentosum group A) protein specifically recognizes the UV-orchemically damaged DNA lesions, and triggers thenucleotide excision repair process. XPA binds to thereplication protein A (RPA) or the excision repaircross complementing 1 protein (ERCC 1). In the absence of nucleotide excision repair persisting(unrepaired) DNA lesions (adducts) may lead to the accumulation of gene mutations and ultimately to cancer. Xeroderma pigmentosum patients have a >2000 fold increased risk to develop skin cancer atsun-exposed areas. |
(This product is for In Vitro experimental use only.)
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PO
Box 117, Rockford, IL 61105 USA |
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