Anti-ABCC2 Monoclonal Antibody
Printable Datasheet
Synonyms:
Human MRP2
Entrez Gene ID:
(Human) 1244
UniProt ID:
Q92887
| Details | |
| Host / Isotype: | Mouse / IgG2b |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | M2III-5 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Human MRP2. |
| Ordering Information | ||||
| Pierce Anti-ABCC2 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-35678 | 1 ml | $531.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 1 ml serum-free tissue cµlture supernatant (250 µg immunoglobµlin/ml) in 0.7% BSA and 0.1% sodium azide. |
| Applications | Dilution |
| Flow Cytometry (FACS) | Assay dependent. |
| Immunocytochemistry (ICC) | 1:20 - 1:50 |
| Immunohistochemistry (Paraffin, Frozen) (IHC (P, F)) | 1:20 |
| Western Blot (WB) | 1:20 - 1:50 |
| Product Specific Information |
| MA1-35678 detects ABCC2 in human samples. MA1-35678 has been successfully used in immunohistochemistry (paraffin, frozen), flow cytometry, western blotting and immunocytochemistry applications. For immunohistochemistry (paraffin), pretreat antibody with 0.01 M citric acid, pH 6.0, in distilled water at 100ºc for 5 minutes, three times. The MA1-35678 immunogen is from human MRP2. |
| General Information |
| M2III-5 reacts with an internal epitope of MRP2, a 190-200 kD transmembrane protein earlier known as the canalicular multi-organic anion transporter cMOAT, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. MRP2 is a member of the MRP family of multidrug resistance related proteins, and MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. M2III-5 was raised against a fusion protein of the bacterial maltose binding protein and rat Mrp2, containing the 202-amino acid COOH terminal end of the transporter protein. |
(This product is for In Vitro experimental use only.)
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PO
Box 117, Rockford, IL 61105 USA |
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