Anti-ABCC2 Monoclonal Antibody
| Host / Isotype: |
Mouse / IgG2b |
| Class: |
Monoclonal |
| Type: |
Antibody |
| Clone: |
M2III-5 |
| Label: |
|
| Species Reactivity: |
Human (Hu) |
| Immunogen: |
Human MRP2. |
|
| Flow Cytometry (FACS) |
Assay dependent. |
| Immunocytochemistry (ICC) |
1:20 |
| Immunohistochemistry (Paraffin, Frozen) (IHC (P, F)) |
1:20 |
| Western Blot (WB) |
1:20 |
| Pierce Anti-ABCC2 Monoclonal Antibody |
|
| Product Number |
Pkg Size |
Price |
|
|
| MA1-35678 |
1 ml |
$531.00 |
|
|
|
|
| Storage: |
-20 °C, Avoid Freeze/Thaw Cycles |
| Form: |
1 ml serum-free tissue cµlture supernatant (250 µg immunoglobµlin/ml) in 0.7% BSA and 0.1% sodium azide. |
MA1-35678 detects ABCC2 in human samples.
MA1-35678 has been successfully used in immunohistochemistry (paraffin, frozen), flow cytometry, western blotting and immunocytochemistry applications.
The MA1-35678 immunogen is from human MRP2. |
ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.
|
No references for this product. |
This product is for In Vitro experimental use only
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