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Anti-ABCG2 Monoclonal Antibody

Printable Datasheet

Details
Host / Isotype: Rat / IgG1
Class: Monoclonal
Type: Antibody
Clone: BXP-9
Label:
Species Reactivity: Murine (Ms)
Immunogen: Fusion protein composed of the E. coli maltose binding protein andmouse bcrp protein (residues 221-394).
Applications Dilution
Flow Cytometry (FACS) Assay dependent.
Immunocytochemistry (ICC) 1:20
Immunohistochemistry (IHC) 1:20
Western Blot (WB) 1:20
Ordering Information
Pierce Anti-ABCG2 Monoclonal Antibody
Product Number Pkg Size Price


MA1-35032 1 ml $531.00
Storage: -20 °C, Avoid Freeze/Thaw Cycles
Form: 1 ml serum-free tissue cµlture supernatant (250 µg immunoglobµlin/ml) in 0.7% BSA and 0.1% sodium azide.


Product Specific Information General Information
MA1-35032 detects ABCG2 in mouse samples.

MA1-35032 has been successfully used in immunocytochemistry, immunohistochemistry, western blotting and flow cytometry applications.

The MA1-35032 immunogen is from a fusion protein containing the E coli maltose binding protein and a fragment of the mouse bcrp protein corresponding to amino acids 221-394.
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.
References:

No references for this product.

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