Anti-ABCG2 Monoclonal Antibody
| Host / Isotype: |
Rat / IgG1 |
| Class: |
Monoclonal |
| Type: |
Antibody |
| Clone: |
BXP-9 |
| Label: |
|
| Species Reactivity: |
Murine (Ms) |
| Immunogen: |
Fusion protein composed of the E. coli maltose binding protein andmouse bcrp protein (residues 221-394). |
|
| Flow Cytometry (FACS) |
Assay dependent. |
| Immunocytochemistry (ICC) |
1:20 |
| Immunohistochemistry (IHC) |
1:20 |
| Western Blot (WB) |
1:20 |
| Pierce Anti-ABCG2 Monoclonal Antibody |
|
| Product Number |
Pkg Size |
Price |
|
|
| MA1-35032 |
1 ml |
$531.00 |
|
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| Storage: |
-20 °C, Avoid Freeze/Thaw Cycles |
| Form: |
1 ml serum-free tissue cµlture supernatant (250 µg immunoglobµlin/ml) in 0.7% BSA and 0.1% sodium azide. |
MA1-35032 detects ABCG2 in mouse samples.
MA1-35032 has been successfully used in immunocytochemistry, immunohistochemistry, western blotting and flow cytometry applications.
The MA1-35032 immunogen is from a fusion protein containing the E coli maltose binding protein and a fragment of the mouse bcrp protein corresponding to amino acids 221-394. |
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.
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No references for this product. |
This product is for In Vitro experimental use only