Anti-ABCG2 Monoclonal Antibody
Printable Datasheet
Synonyms:
BCRP
Entrez Gene ID:
(Human) 9429
UniProt ID:
Q9UNQ0
| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | BXP-34 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | MCF7 MR cell line, over-expressing ABCG2. |
| Ordering Information | ||||
| Pierce Anti-ABCG2 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-35030 | 1 ml | $636.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 1 ml antibody (250 µg/ml) in 1% BSA and 0.1% sodium azide. |
| Applications | Dilution |
| Flow Cytometry (FACS) | 1:20 |
| Immunocytochemistry (ICC) | 1:20 - 1:50 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:20 |
| Product Specific Information |
| MA1-35030 detects ABCG2 in human samples.BXP-34 did not cross react with the human MDR1, MRP1, MRP2, MRP5 gene products. MA1-35030 has been successfully used in immunohistochemistry (frozen), flow cytometry and immunocytochemistry applications. MA1-35030 is known to be unreactive in Western blot and immunohistochemistry(paraffin) applications. The MA1-35030 immunogen is from a proprietary immunogen. |
| General Information |
| The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. |
(This product is for In Vitro experimental use only.)
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Box 117, Rockford, IL 61105 USA |
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