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Anti-Blood Group H1 (O) Antigen Monoclonal Antibody

Details
Host / Isotype: Mouse / IgG3
Class: Monoclonal
Type: Antibody
Clone: 17-206
Species Reactivity: Human (Hu)
Immunogen: SW-403 human colon cancer cell line.
Ordering Information
Pierce Anti-Blood Group H1 (O) Antigen Monoclonal Antibody
Product Number Pkg. Size Price Purchase
MA1-26521 500 µl $370.87  


Storage: 4º C, DO NOT FREEZE!
Form: 500 µl of unpurified ascites in 0.01 M PBS with 0.1% sodium azide and 1% BSA.


Applications Dilution
Immunohistochemistry (Paraffin) (IHC (P)) 1:40
Product Specific Information
MA1-26521 detects Blood Group Antigen H (O) Type 1 (BG4) from human samples. This antibody not cross-react with the H blood group substance of the Type 2 backbone.

MA1-26521 has been successfully used in immunohistochemistry (paraffin) procedures.

The MA1-26521 immunogen is SW-403 human colon cancer cell line.

Positive Control: Kidney or antrum (human).
General Information
Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood Group H1 (O) is one of a series of well characterised murine monoclonal antibodies detecting blood group specificities of the ABH and Lewis systems. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
(This product is for In Vitro experimental use only.)


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