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CADHERIN E ANTIBODIES > CADHERIN E MONOCLONAL ANTIBODY MA1-26239
Anti-Cadherin E Monoclonal Antibody
Printable Datasheet
Synonyms:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Entrez Gene ID:
(Human) 999
UniProt ID:
P12830
| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | 67A4 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Human breast carcinoma cell line T471. |
| Ordering Information | ||||
| Pierce Anti-Cadherin E Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-26239 | 250 µl | $378.00 | ||
| Storage: | 4º C |
| Form: | 250 µl of tissue culture supernatant antibody (0.125 mg/ml) with sodium azide. |
| Applications | Dilution |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:25 - 1:50 |
| Product Specific Information |
| MA1-26239 detects E Cadherin from human samples. MA1-26239 has been successfully used in immunohistochemistry (frozen) procedures. The MA1-26239 immunogen is human breast carcinoma cell line T471. |
| General Information |
| This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. |
(This product is for In Vitro experimental use only.)
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