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ACYL-COA DESATURASE (SCD) ANTIBODIES > ACYL-COA DESATURASE (SCD) MONOCLONAL ANTIBODY MA1-26155
Anti-Acyl-CoA Desaturase (SCD) Monoclonal Antibody
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Synonyms:
PRO1933, FADS5, MSTP008, SCD1, SCDOS
Entrez Gene ID:
(Human) 6319
UniProt ID:
O00767
| Details | |
| Host / Isotype: | Mouse / IgG2b |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | CD.E10 |
| Species Reactivity: | Human (Hu) Murine (Ms) |
| Immunogen: | Recombinant, full length human protein. |
| Ordering Information | ||||
| Pierce Anti-Acyl-CoA Desaturase (SCD) Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-26155 | 100 µg | $403.00 | ||
| Storage: | 4º C |
| Form: | 100 µg of IgG fraction antibody (1 mg/ml) in PBS (pH 7.4) with 0.05% sodium azide. |
| Applications | Dilution |
| ELISA (ELISA) | Assay Dependent |
| Immunohistochemistry (IHC) | Assay Dependent |
| Immunoprecipitation (IP) | Assay Dependent |
| Western Blot (WB) | Assay Dependent |
| Product Specific Information |
| MA1-26155 detects SCD from human and mouse samples. MA1-26155 has been successfully used in ELISA, Immunohistochemistry, immunoprecipitation, and Western blot procedures. Predicted molecular weight is 41.5 kDa. The MA1-26155 immunogen is recombinant, full length human protein. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze/thaw cycles. |
| General Information |
| Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5 ., have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Zhang et al. (1999) [PubMed 10229681]; Wang et al., 2005 [PubMed 15907797])., , |
(This product is for In Vitro experimental use only.)
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