| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | 26C593 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide, conjugated to KLH, corresponding to residues 268-284 of TLR9. |
| Ordering Information | ||||
| Pierce Anti-TLR9 DISCONTINUED DISCONTINUED Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-25436 | 50 µg | $0.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 50 µg of Protein G purified antibody (0.5 mg/ml) in PBS with 0.02% sodium azide. |
| Applications | Dilution |
| Western Blot (WB) | 1 - 2 µg/ml |
| Product Specific Information |
| MA1-25436 detects TLR9 from human samples. MA1-25436 has been successfully used in Western blot procedures. The MA1-25436 immunogen is a synthetic peptide, conjugated to KLH, corresponding to residues 268-284 of TLR9. |
| General Information |
| The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. |
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