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Anti-Vinculin Monoclonal Antibody

Synonyms:
RP11-178G16.3, CMD1W, MVCL
Entrez Gene ID:
(Human) 7414, (Murine) 22330, (Rat) 305679, (Bovine) 783645
UniProt ID:
P18206
Details
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Clone: hVIN-1
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt) Canine (Ca) Bovine (Bv) Chicken (Ck) Avian (Av) Xenopus laevis (Xl)
Immunogen: Purified, full length, native human protein.
Ordering Information
Pierce Anti-Vinculin Monoclonal Antibody
Product Number Pkg. Size Price Purchase
MA1-25018 200 µl $440.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 200 µl of ascites antibody with 15 mM sodium azide.


Applications Dilution
Immunofluorescence (IF) 1:400
Immunohistochemistry (Frozen) (IHC (F)) Assay Dependent
Western Blot (WB) Assay Dependent
Product Specific Information
MA1-25018 detects Vinculin from human, mouse, rat, Xenopus laevis, bovine, chicken, canine, and turkey samples.

MA1-25018 has been successfully used in immunohistochemistry (frozen), and Western blot procedures.

The MA1-25018 immunogen is purified, full length, native human protein.
General Information
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
(This product is for In Vitro experimental use only.)


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