Anti-RAD51 Monoclonal Antibody
Printable Datasheet
Synonyms:
BRCC5, HRAD51, HsRad51, HsT16930, RAD51A, RECA
Entrez Gene ID:
(Human) 5888
UniProt ID:
Q06609
| Details | |
| Host / Isotype: | Mouse / IgG2b |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | 14B4 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Full length Rad51 protein (amino acids 1-338) expressed in E. coli. |
| Ordering Information | ||||
| Pierce Anti-RAD51 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-23271 | 100 µg | $358.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg (1.0 mg/ml) of Protein G affinity purified antibody in PBS, pH 7.4. |
| Applications | Dilution |
| Immunofluorescence (IF) | Assay dependent |
| Immunoprecipitation (IP) | Assay dependent |
| Western Blot (WB) | 1:500 - 1:2,000 |
| Product Specific Information |
| MA1-23271 detects Rad51 in human samples. MA1-23271 has been successfully used in immunofluorescence, immunoprecipitation and Western blot procedures. The MA1-23271 immunogen is full length Rad51 protein (amino acids 1-338) expressed in E. coli. |
| General Information |
| Rad51, a 37 kDa protein, is the human homologue of E. coli RecA protein and a member of the RAD52 epistasis group in S. cerevisiae. In recent studies it has been reported that BRCA1 interacts with Rad51 and disease-causing mutations have been found in the BRCA1 region necessary for BRCA1/Rad51 interaction, implying that this interaction is important for tumor suppression. BRCA2 and Rad51 have also been shown to interact by direct binding of the BRC repeats located within exon 11 of BRCA2. When these repeats are deleted, the interaction is lost and cells become hypersensitive to the DNA damage caused by methyl methanesulfonate (MMS). |
(This product is for In Vitro experimental use only.)
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Box 117, Rockford, IL 61105 USA |
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