Part of Thermo Fisher Scientific
HOME >
PROCALCITONIN ANTIBODIES > PROCALCITONIN MONOCLONAL ANTIBODY MA1-20292
Anti-Procalcitonin Monoclonal Antibody
Printable Datasheet| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | 38F11 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Recombinant fragment of human procalcitonin. |
| Ordering Information | ||||
| Pierce Anti-Procalcitonin Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-20292 | 100 µg | $357.00 | ||
| Storage: | 4º C |
| Form: | 100 µg (2 mg/ml) of Protein A purified antibody in PBS with 0.1% sodium azide; pH 7.4. |
| Applications | Dilution |
| ELISA (ELISA) | Assay dependent |
| Western Blot (WB) | Assay dependent |
| Product Specific Information |
| MA1-20292 detects procalcitonin in human samples. MA1-20292 has been successfully used in ELISA and Western blot procedures. The MA1-20292 immunogen is a recombinant fragment of human procalcitonin. |
| General Information |
| Procalcitonin (PCT) is a 116 amino acid residue peptide with molecular weight of ~ 13 kDa. It belongs to a group of related proteins including calcitonin gene-related peptides I and II, amylin, adrenomodulin and calcitonin (CAPA peptide family). PCT, like other peptides of CAPA family, appears from the common precursor pre-procalcitonin consisting of 141 amino acids by removal of 25 a.a.r. from N-terminus. PCT is produced normally in C-cells of the thyroid glands. It undergoes successive cleavages to form three molecules: N-terminal fragment (55 a.a.r.), calcitonin (32 a.a.r.) and katacalcin (21 a.a.r.). It has been shown that the level of PCT is considered to be one of the earliest and most specific markers of sepsis. However, several studies revealed that elevated PCT level in human blood could be detected not only in cases of sepsis and infection, but also in cases of surgery, polytrauma, heat shock and cardiogenic shock (Meisner M. & Reinhart K.). The importance of PCT measurements in combination with cTnT or cTnl during heart transplation to predict an early graft failure has been proved (Potapov EV., et al). |
(This product is for In Vitro experimental use only.)
 |
|||||||||||||
PO
Box 117, Rockford, IL 61105 USA |
 |
 |
