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Anti-CD105 Monoclonal Antibody, FITC conjugate

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Synonyms:
Endoglin
Entrez Gene ID:
(Human) 2022
UniProt ID:
P17813
Details
Host / Isotype: Mouse / IgG2a
Class: Monoclonal
Type: Antibody
Clone: MEM-226
Label: FITC
Species Reactivity: Human (Hu)
Immunogen: Recombinant virus containing the human CD105 cDNA.
Ordering Information
Pierce Anti-CD105 Monoclonal Antibody, FITC conjugate
Product Number Pkg. Size Price Purchase
MA1-19594 100 Tests $322.00


Storage: 4º C, store in dark, DO NOT FREEZE!
Form: 100 tests of FITC conjugated antibody in PBS with 15 mM sodium azide and 0.2% (w/v) high-grade protease free BSA.


Applications Dilution
Flow Cytometry (FACS) 20 ul/10^6 cells
Product Specific Information
MA1-19594 detects CD105 in human samples.

MA1-19594 has been successfully used in FACS procedures.

The MA1-19594 immunogen is recombinant virus containing the human CD105 cDNA.
General Information
CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFßR-2 as a receptor for TGFß-1 and TGFß-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFß-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.
Flow Cytometry with anti-CD105 Monoclonal Antibody [MEM-226], FITC conjugate (MA1-19594)
(This product is for In Vitro experimental use only.)


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