Part of Thermo Fisher Scientific

Anti-CD105 Monoclonal Antibody

Synonyms:
Endoglin
Entrez Gene ID:
(Human) 2022
UniProt ID:
P17813
Details
Host / Isotype: Mouse / IgG2a
Class: Monoclonal
Type: Antibody
Clone: MEM-229
Species Reactivity: Human (Hu) Porcine (Po)
Immunogen: Recombinant Vaccinia virus containing human CD105 (L-isoform) cDNA.
Ordering Information
Pierce Anti-CD105 Monoclonal Antibody
Product Number Pkg. Size Price Purchase
MA1-19408 100 µg $322.00


Storage: 4º C
Form: 100 µg of Protein A affinity purified antibody (1mg/ml) in PBS with 15 mM sodium azide pH 7.4.


Applications Dilution
Flow Cytometry (FACS) 10 µg/ml
Western Blot (WB) Assay Dependent
Product Specific Information
MA1-19408 detects CD105 in human and porcine samples.

MA1-19408 has been successfully used in FACS and Western blot (non-reducing) procedures.

The MA1-19408 immunogen is recombinant vaccinia virus containing human CD105 (L-isoform) cDNA.

Store at 2-8ºC. For long term storage, aliquot and store at -20ºC, avoiding freeze/thaw cycles.
General Information
CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFßR-2 as a receptor for TGFß-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antogonises the inhibitory effects of THFß-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.
(This product is for In Vitro experimental use only.)


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