Anti-CD105 Monoclonal Antibody
Printable Datasheet
Synonyms:
Endoglin
Entrez Gene ID:
(Human) 2022
UniProt ID:
P17813
| Details | |
| Host / Isotype: | Mouse / IgG2a |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | MEM-229 |
| Species Reactivity: | Human (Hu) Porcine (Po) |
| Immunogen: | Recombinant Vaccinia virus containing human CD105 (L-isoform) cDNA. |
| Ordering Information | ||||
| Pierce Anti-CD105 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-19408 | 100 µg | $322.00 | ||
| Storage: | 4º C |
| Form: | 100 µg of Protein A affinity purified antibody (1mg/ml) in PBS with 15 mM sodium azide pH 7.4. |
| Applications | Dilution |
| Flow Cytometry (FACS) | 10 µg/ml |
| Western Blot (WB) | Assay Dependent |
| Product Specific Information |
| MA1-19408 detects CD105 in human and porcine samples. MA1-19408 has been successfully used in FACS and Western blot (non-reducing) procedures. The MA1-19408 immunogen is recombinant vaccinia virus containing human CD105 (L-isoform) cDNA. Store at 2-8ºC. For long term storage, aliquot and store at -20ºC, avoiding freeze/thaw cycles. |
| General Information |
| CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFßR-2 as a receptor for TGFß-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antogonises the inhibitory effects of THFß-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels. |
(This product is for In Vitro experimental use only.)
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Box 117, Rockford, IL 61105 USA |
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