| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | HIT2 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Fetal human thymocytes. |
| Ordering Information | ||||
| Pierce Anti-CD38 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-19316 | 100 µg | $322.00 | ||
| Storage: | 4º C |
| Form: | 100 µg of protein G purified antibody (1 mg/ml) in PBS with 15mM sodium azide pH 7.4. |
| Applications | Dilution |
| Flow Cytometry (FACS) | Assay Dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay Dependent |
| Product Specific Information |
| MA1-19316 detects CD38 in human samples. MA1-19316 has been successfully used in FACS, Western blot and immunohistochemistry (Frozen) procedures. The MA1-19316 immunogen is fetal human thymocytes. Store at 2-8ºC. For long term storage, aliquot and store at -20ºC, avoiding freeze/thaw cycles. |
| General Information |
| CD38 (T10) is a single chain 46 kDa type II integral glycoprotein with a short N terminal cytoplasmic tail. CD38 is highly expressed on thymocytes. It is also expressed by early cells of B and T lineages, NK cells, plasma cells, monocytes and macrophages and may be detected on cells from multiple myeloma, ALL (B and T) and some AML. In normal lymph nodes and tonsils the antigen is detected mainly on B cells in germinal centers and in plasma cells. The extracellular domain of the molecule shares a high homology sequence with Aplysia ADP ribosyl cyclase. CD38 functions as a multicatalytic ectoenzyme serving as ADP ribosyl cyclase, ADPR hydrolase and possibly NAD+ glycohydrolase, or as a surface receptor. |
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Box 117, Rockford, IL 61105 USA |
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