Anti-CD11b Monoclonal Antibody
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Synonyms:
Mac-1
Entrez Gene ID:
(Human) 3684
UniProt ID:
P11215
| Details | |
| Host / Isotype: | Mouse / IgG2a |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | MEM-174 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Human granulocytes. |
| Ordering Information | ||||
| Pierce Anti-CD11b Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-19004 | 100 µg | $268.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of antibody in Azide free phosphate buffered saline (PBS), preserved by filter sterilization pH 7.4. |
| Applications | Dilution |
| Flow Cytometry (FACS) | Assay Dependent |
| Immunoprecipitation (IP) | Assay Dependent |
| Product Specific Information |
| MA1-19004 detects CD11b in human samples. MA1-19004 has been successfully used in FACS and immunoprecipitation procedures. The MA1-19004 immunogen is human granulocytes. |
| General Information |
| CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical with CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8% spleen cells, 44% bone marrow cells and less than 1% of thymocytes. |
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Immunoprecipitation with anti-CD11b Monoclonal Antibody [MEM-174] (MA1-19004)
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(This product is for In Vitro experimental use only.)
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PO
Box 117, Rockford, IL 61105 USA |
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