Anti-ABCA1 Monoclonal Antibody
| Host / Isotype: |
Rat / IgG2a, kappa |
| Class: |
Monoclonal |
| Type: |
Antibody |
| Clone: |
5A1-1422.11 |
| Label: |
|
| Species Reactivity: |
Murine (Ms) |
| Immunogen: |
Mouse ABCA1-expressing HeLa stable transfectants. |
|
| Flow Cytometry (FACS) |
1:1000 |
| Pierce Anti-ABCA1 Monoclonal Antibody |
|
| Product Number |
Pkg Size |
Price |
|
|
| MA1-16937 |
100 µl |
$343.00 |
|
|
|
|
| Storage: |
-20º C, Avoid Freeze/Thaw Cycles |
| Form: |
100 µl (29 mg/ml) of whole antisera rat ascites containing 0.1% sodium azide. |
MA1-16937 detects ABCA1 protein in mouse samples.
MA1-16937 has been successfully used in flow cytometry procedures. This antibody is not reactive in Western blot or ELISA applications.
MA1-16937 immunogen is mouse ABCA1-expressing HeLa stable transfectants.
Figure 1 shows a FACS analysis of Raw (red) and Raw-cAMP (blue) cells using MA1-16937. |
Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI. |
No references for this product. |
This product is for In Vitro experimental use only
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