Anti-MMP9 Monoclonal Antibody
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Synonyms:
MMP-9
Entrez Gene ID:
(Human) 4318
UniProt ID:
P14780
| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | 2C3 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide derived from the c-teminus of the human MMP-9 protein and mouse myeloma Ag 8563 cells. |
| Ordering Information | ||||
| Pierce Anti-MMP9 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-12894 | 200 µg | $332.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 200 µg antibody in PBS with 0.08% sodium azide. |
| Applications | Dilution |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1 - 5 ug/ml |
| Western Blot (WB) | 1-2 µg/ml |
| Product Specific Information |
| MA1-12894 detects Matrix Metalloproteinase 9 in human samples. MA1-12894 has been successfully used in western blot and immunohistochemistry (paraffin) procedures. Suggested positive control of colon, esophagel or gastric tissues. The MA1-12894 immunogen is a synthetic peptide derived from the c-teminus of the human MMP-9 protein and mouse myeloma Ag 8563 cells. |
| General Information |
| Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. |
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Immunohistochemistry with anti-MMP9 Monoclonal Antibody [2C3] (MA1-12894)
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(This product is for In Vitro experimental use only.)
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PO
Box 117, Rockford, IL 61105 USA |
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