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Anti-MMP3 Monoclonal Antibody

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Synonyms:
MMP-3
Entrez Gene ID:
(Human) 4314
UniProt ID:
P08254
Details
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Clone: 1B4
Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide corresponding to human MMP3.
Ordering Information
Pierce Anti-MMP3 Monoclonal Antibody
Product Number Pkg. Size Price Purchase
MA1-12893 200 µg $332.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 200 µg in PBS with 0.08% sodium azide.


Applications Dilution
ELISA (ELISA) Assay Dependent
Immunohistochemistry (IHC) 1:100
Western Blot (WB) 1:100
Product Specific Information
MA1-12893 detects Matrix Metalloproteinase 3 in human samples.

MA1-12893 has been successfully used in ELISA, western blot and immunohistochemistry procedures.

The MA1-12893 immunogen is a synthetic peptide corresponding to human MMP3.
General Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Immunohistochemistry with anti-MMP3 Monoclonal Antibody [1B4] (MA1-12893)
(This product is for In Vitro experimental use only.)


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