Anti-MMP2 Monoclonal Antibody
Printable Datasheet
Synonyms:
MMP-2
Entrez Gene ID:
(Human) 4313
UniProt ID:
P08253
| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | 4D3 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide corresponding to human MMP2. |
| Ordering Information | ||||
| Pierce Anti-MMP2 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-12892 | 200 µg | $332.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 200 µg antibody in PBS with 0.08% sodium azide. |
| Applications | Dilution |
| ELISA (ELISA) | Assay Dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1-5 µg/ml |
| Western Blot (WB) | 1-2 µg/ml |
| Product Specific Information |
| MA1-12892 detects Matrix Metalloproteinase 2 in human samples. MA1-12892 has been successfully used in ELISA, western blot and immunohistochemistry procedures. The MA1-12892 immunogen is a synthetic peptide corresponding to human MMP2. |
| General Information |
| Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. |
(This product is for In Vitro experimental use only.)
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Box 117, Rockford, IL 61105 USA |
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