| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | NSF-1 |
| Species Reactivity: | Human (Hu) Murine (Ms) Rat (Rt) Bovine (Bv) Chicken (Ck) |
| Immunogen: | Recombinant human NSF. |
| Ordering Information | ||||
| Pierce Anti-NSF Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-12435 | 100 µg | $268.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg containing 20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol at pH 7.5 and 3 mM sodium azide. |
| Applications | Dilution |
| ELISA (ELISA) | Assay Dependent |
| Immunoprecipitation (IP) | Assay Dependent |
| Western Blot (WB) | Assay Dependent |
| Product Specific Information |
| MA1-12435 detects NSF in human, mouse, rat and bovine and chicken samples. MA1-12435 has been successfully used in ELISA, western blot and immunoprecipitation procedures. The MA1-12435 immunogen is recombinant human NSF. |
| General Information |
| NSF (N-ethylmaleimide sensitive fusion protein) is a critical component of the SNARE (soluble NSF attachment protein receptors) protein complex that is involved in synaptic vesicle trafficking. Specifically, NSF has been found to be essential in membrane fusion. Furthermore, NSF has been recently demonstrated to bind other protein complexes such as AMPA receptor subunits (GluR2), GATE-16, LMA-1 and Rabs suggesting a more diverse role in the assembly of various protein complexes (Whiteheart et al., 2004). |
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