| Details | |
| Host / Isotype: | Mouse / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | 1H7 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Purified human placental IGF-1 receptors. |
| Ordering Information | ||||
| Pierce Anti-IGF1 Receptor Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-10854 | 100 ug | $268.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of protein G purified antibody (0.3 mg/ml) in phosphate-buffered saline, pH 7.4. |
| Applications | Dilution |
| Western Blot (WB) | Assay dependent |
| Product Specific Information |
| MA1-10854 detects IGF-1 Receptor from human samples. MA1-10854 has been successfully used in Western blot applications. Dilute in PBS or medium which is identical to that used in the assay system. The MA1-10854 immunogen is purified human placental IGF-1 receptors. |
| General Information |
| This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. |
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Box 117, Rockford, IL 61105 USA |
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