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INTEGRIN BETA-1D ANTIBODIES > INTEGRIN BETA-1D MONOCLONAL ANTIBODY MA1-06906
Anti-Integrin beta-1d Monoclonal Antibody
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Synonyms:
CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB
Entrez Gene ID:
(Human) 3688, (Murine) 16412
UniProt ID:
P05556
| Details | |
| Host / Isotype: | Mouse / IgG1, kappa |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | 2B1 |
| Species Reactivity: | Human (Hu) Murine (Ms) Canine (Ca) |
| Immunogen: | Synthetic peptide corresponding to residues C Q(56) E N P I Y K S P I N N F K N P N Y G R K A G L(79) of mouse integrin beta 1D. |
| Ordering Information | ||||
| Pierce Anti-Integrin beta-1d Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-06906 | 100 µg | $342.00 | ||
| Storage: | 4º C |
| Form: | 100 µg of purified antibody (1 mg/ml) in PBS containing 0.09% sodium azide. |
| Applications | Dilution |
| Immunocytochemistry (ICC) | Assay dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:25 - 1:200 |
| Western Blot (WB) | 1:100 - 1:1000 |
| Product Specific Information |
| MA1-06906 detects integrin beta-1D in human, canine and mouse samples. MA1-06906 has sucessfully been used in immunocytochemistry, immunohistochemistry, and Western blotting procedures. The MA1-06906 immunogen is a synthetic peptide corresponding to the residues C Q(56) E N P I Y K S P I N N F K N P N Y G R K A G L(79) of the cytoplasmic domain of mouse integrin subunit b1D. Store at 4ºC or in small aliquots at -20ºC. Figure 1 illustrates immunostaining of integrin beta-1D in rat heart muscle cells using MA1-06906. |
| General Information |
| Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated alpha and beta subunits. More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. There are two major forms of integrin beta1: beta1A and beta1D, which differ in 13 amino acids. Their distribution pattern in adult tissues is mutually exclusive. beta1A is present in all tissues, except cardiac and skeletal muscle, which instead express the beta1D variant. |
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Immunofluorescence with anti-Integrin beta-1d Monoclonal Antibody [2B1] (MA1-06906)
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(This product is for In Vitro experimental use only.)
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Box 117, Rockford, IL 61105 USA |
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