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Anti-Cytokeratin 14 Monoclonal Antibody

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Synonyms:
Keratin-14, CK-14, K14 Synonyms Cytokeratin-14 CK-14 Keratin-14 K14, Keratin-14, CK-14
Entrez Gene ID:
(Human) 3861
UniProt ID:
P02533
Details
Host / Isotype: Mouse
Class: Monoclonal
Type: Antibody
Clone: RCK107
Species Reactivity: Human (Hu) Rat (Rt) Canine (Ca) Porcine (Po)
Immunogen: Cytoskeletal preparation of TR146 epithelial cells.
Ordering Information
Pierce Anti-Cytokeratin 14 Monoclonal Antibody
Product Number Pkg. Size Price Purchase
MA1-06323 100 µg $342.00


Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 µg of antibody (1 mg/ml) in culture supernatant with 0.09% sodium azide.


Applications Dilution
Immunocytochemistry (ICC) Assay dependent
Immunohistochemistry (Frozen) (IHC (F)) Assay dependent
Western Blot (WB) Assay dependent
Product Specific Information
MA1-06323 detects cytokeratin 14 in human, rat, canine, and porcine samples.

MA1-06323 has sucessfully been used in Western blotting, immunocytochemistry and immunohistochemistry.

The MA1-06323 immunogen is a cytoskeletal preparation of TR146 epithelial cells.

Figure 1 illustrates immunostaining of cytokeratin 14 in the basal cell compartment of human skin samples using MA1-06323.
General Information
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ~40 kDa and ~68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
Immunohistochemistry with anti-Cytokeratin 14 Monoclonal Antibody [RCK107] (MA1-06323)
(This product is for In Vitro experimental use only.)


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