| Details | |
| Host / Isotype: | Mouse |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | RCK107 |
| Species Reactivity: | Human (Hu) Rat (Rt) Canine (Ca) Porcine (Po) |
| Immunogen: | Cytoskeletal preparation of TR146 epithelial cells. |
| Ordering Information | ||||
| Pierce Anti-Cytokeratin 14 Monoclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| MA1-06323 | 100 µg | $342.00 | ||
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of antibody (1 mg/ml) in culture supernatant with 0.09% sodium azide. |
| Applications | Dilution |
| Immunocytochemistry (ICC) | Assay dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay dependent |
| Western Blot (WB) | Assay dependent |
| Product Specific Information |
| MA1-06323 detects cytokeratin 14 in human, rat, canine, and porcine samples. MA1-06323 has sucessfully been used in Western blotting, immunocytochemistry and immunohistochemistry. The MA1-06323 immunogen is a cytoskeletal preparation of TR146 epithelial cells. Figure 1 illustrates immunostaining of cytokeratin 14 in the basal cell compartment of human skin samples using MA1-06323. |
| General Information |
| Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ~40 kDa and ~68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. |
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Box 117, Rockford, IL 61105 USA |
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