Anti-CAD Polyclonal Antibody
Printable Datasheet
Synonyms:
RP13-531C17.1, CAD, CPAN, DFF-40, DFF2, DFF40
Entrez Gene ID:
(Human) 1677
UniProt ID:
O76075
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide |
| Ordering Information | ||||
| Pierce Anti-CAD Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| LF-PA0057 | 100 µl | $285.00 | ||
This product is not available outside of the U.S.
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µl of antibody in HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
| Applications | Dilution |
| Western Blot (WB) | Assay Dependent |
| Product Specific Information |
| LF-PA0057 detects CAD from human samples. LF-PA0057 has been successfully used in WB procedures. The LF-PA0057 immunogen is a synthetic peptide |
| General Information |
| Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of these variants has not been determined. |
(This product is for In Vitro experimental use only.)
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Box 117, Rockford, IL 61105 USA |
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