| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Purified recombinant human MMP2 protein. |
| Ordering Information | ||||
| Pierce Anti-MMP2 Polyclonal Antibody | ||||
| Product Number | Pkg. Size | Price | Purchase | |
| GB-10342 | 250 µl | $319.00 | ||
This product is not available outside of the U.S.
| Storage: | -20º C, Avoid Freeze/Thaw Cycles |
| Form: | 250 µl of antibody provided as crude antiserum |
| Applications | Dilution |
| Western Blot (WB) | 1:1,000 |
| Product Specific Information |
| GB-10342 detects MMP-2 in human samples. GB-10342 has been successfully used in Western blot procedures. The GB-10342 immunogen recombinant human MMP2 protein. |
| General Information |
| Loss of negative growth regulation and high invasive potential are neoplastic traits often associated with abnormal expression of matrix matalloproteinases. MMP-2, the signalling mechanism for cells to begin migration, triggers the movement when it splits laminin-5 and exposes and integrin-binding site on this component of epithelial basement membrane. The changed form of laminin was found in tumors and in tissues being altered. The activated form of MMP2, however, is not found in benign tumors. Thus detection of the enzyme is a possible early indicator of tumor activity. |
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Box 117, Rockford, IL 61105 USA |
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