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Anti-MMP2 Polyclonal Antibody

Synonyms:
Matrix Metalloproteinase 2
Entrez Gene ID:
(Human) 4313
UniProt ID:
P08253
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Purified recombinant human MMP2 protein.
Ordering Information
Pierce Anti-MMP2 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
GB-10342 250 µl $319.00

This product is not available outside of the U.S.



Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 250 µl of antibody provided as crude antiserum


Applications Dilution
Western Blot (WB) 1:1,000
Product Specific Information
GB-10342 detects MMP-2 in human samples.

GB-10342 has been successfully used in Western blot procedures.

The GB-10342 immunogen recombinant human MMP2 protein.
General Information
Loss of negative growth regulation and high invasive potential are neoplastic traits often associated with abnormal expression of matrix matalloproteinases. MMP-2, the signalling mechanism for cells to begin migration, triggers the movement when it splits laminin-5 and exposes and integrin-binding site on this component of epithelial basement membrane. The changed form of laminin was found in tumors and in tissues being altered. The activated form of MMP2, however, is not found in benign tumors. Thus detection of the enzyme is a possible early indicator of tumor activity.
(This product is for In Vitro experimental use only.)


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