Anti-Vascular Endothelial Growth Factor Polyclonal Antibody
This product is not available outside of the U.S.
| Host / Isotype: |
Rabbit |
| Class: |
Polyclonal |
| Type: |
Antibody |
| Clone: |
|
| Label: |
|
| Species Reactivity: |
Human (Hu) Murine (Ms) Rat (Rt) |
| Immunogen: |
Synthetic peptide of human VEGF. |
|
| Pierce Anti-Vascular Endothelial Growth Factor Polyclonal Antibody |
|
| Product Number |
Pkg Size |
Price |
|
|
| GB-10050 |
250 µl |
$319.00 |
|
|
|
|
| Storage: |
-20º C, Avoid Freeze/Thaw Cycles |
| Form: |
250 µl of antibody provided as crude antiserum. |
GB-10050 detects VEGF in human, mouse and rat samples.
GB-10050 has been successfully used in ELISA procedures.
The GB-10050 immunogen is a synthetic peptide of human VEGF located within the putative C2C2 Zinc finger domain. |
The vascular endothelial growth factor (VEGF) family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells. |
No references for this product. |
This product is for In Vitro experimental use only
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