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Anti-Vascular Endothelial Growth Factor Polyclonal Antibody

Synonyms:
Vascular Endothelial Growth Factor, Vascular Permeability Factor, VEGFA, VPF
Entrez Gene ID:
(Human) 7422, (Murine) 22339, (Rat) 83785
UniProt ID:
P15692
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt)
Immunogen: Synthetic peptide of human VEGF.
Ordering Information
Pierce Anti-Vascular Endothelial Growth Factor Polyclonal Antibody
Product Number Pkg. Size Price Purchase
GB-10050 250 µl $319.00

This product is not available outside of the U.S.



Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 250 µl of antibody provided as crude antiserum.


Applications Dilution
ELISA (ELISA) 1:5,000
Product Specific Information
GB-10050 detects VEGF in human, mouse and rat samples.

GB-10050 has been successfully used in ELISA procedures.

The GB-10050 immunogen is a synthetic peptide of human VEGF located within the putative C2C2 Zinc finger domain.
General Information
The vascular endothelial growth factor (VEGF) family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells.
(This product is for In Vitro experimental use only.)


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