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Anti-APC-AAT complexes, neoepitope Monoclonal Antibody

Details
Host / Isotype: Mouse / IgG1, kappa
Class: Monoclonal
Type: Antibody
Clone: 7
Species Reactivity: Human (Hu)
Immunogen: Recombinant form of human activated protein C.
Ordering Information
Pierce Anti-APC-AAT complexes, neoepitope Monoclonal Antibody
Product Number Pkg. Size Price Purchase
ABS 001-07-02 200 µg $429.00


Storage: 4º C, store in dark
Form: 200 µg of Protein A/G purified antibody (1 mg/ml) in 0.01 M phosphate buffer, with 0.5 M NaCl and 15 mM sodium azide; pH 7.4.


Applications Dilution
ELISA (ELISA) 1:500
Product Specific Information
ABS 001-07-02 has specificity for a conformation-dependant neoepitope that is expressed in activated protein C upon complex-formation with alpha1-antitrypsin. No reaction is seen to non-complexed alpha1-antitrypsin and only very little cross reaction to protein C zymogen. Note that specificity is calcium dependent.
 
ABS 001-07-02 has been successfully used in ELISA procedures. ABS 001-07-02 reacts strongly with APC-AAT complexes in ELISA. It can be used in sandwich ELISA in combination with a polyclonal anti-protein C antiserum. Note, that the conformational neoepitope expressed in the complex can also be expressed in APC coated directly onto a high-binding microtiter plate.

The ABS 001-07-02 immunogen is the recombinant form of human activated protein C.

The epitope specificity of ABS 001-07-02 is not determined.
General Information
(This product is for In Vitro experimental use only.)


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